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br Results br Discussion Although they do not have protein
2024-12-25

Results Discussion Although they do not have protein-coding capacity, lncRNAs make up a large part of the transcripts of the genome, and they play fundamental roles in carcinogenesis and osteosarcoma progression through regulation of tumor proliferation and metastasis. These lncRNAs include MA
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Cre mRNA for gene editing In conclusions MPE effects in caus
2024-12-25

In conclusions, MPE effects in causing lesser increase in vaginal fluid pH could partly restore the vaginal acidity in sex-steroid deficient state. MPE could exert its effect via enhancing both H+ generation as well as H+extrusion into the vaginal lumen. Although gallic Cre mRNA for gene editing is
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br Conclusion We have identified potential inhibitors of C a
2024-12-24

Conclusion We have identified potential inhibitors of C. albicans fungus specific nuclear target outer kinetochore Dam1 complex subunit Ask1, virtually screened through the PubChem compounds database (NCBI, USA) by utilizing state-of-art in silico methods in a pipeline. The 3D protein structure o
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The accumulation of oxidized low
2024-12-24

The accumulation of oxidized low-density lipoprotein (oxLDL) is one of the many causes of the initiation and progression of atherosclerosis (Virmani et al., 2002; Pirillo et al., 2013; Sun et al., 2016; Huang et al., 2016; Tabas, 2010). oxLDL-induced apoptosis of macrophages contributes to the forma
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Bran is a byproduct of flour milling
2024-12-24

Bran is a byproduct of flour milling, typically utilized as a valuable component of animal feeds. Because of its attractive technological and health-promoting properties, it Eltrombopag Olamine has also been increasingly used in food manufacturing as a source of dietary fiber. Indeed, with the grow
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kras-pdeδ pathway The fluorescence in a fluorescent antibiot
2024-12-24

The fluorescence in a fluorescent antibiotic can be derived either from functional groups with intrinsic fluorescence in an existing antibiotic, or via synthetic conjugation of a fluorophore to an antibiotic core to enable visualisation. Attachment of fluorophore to an antibiotic should ideally not
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br Telmisartan Telmisartan is one of the widely used
2024-12-24

Telmisartan Telmisartan is one of the widely used antihypertensive agents, which has demonstrated favorable safety and tolerability profiles, both alone and in combination therapies. It has a number of pharmacological properties that distinguish it from other ARBs—the longest plasma half-life, hi
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At the organismal level skeletal muscle lung and adipose tis
2024-12-24

At the organismal level, skeletal muscle, lung and adipose tissues mediate net de novo synthesis and release of glutamine, whereas net glutamine catabolism occurs in the kidney [7]. The liver exhibits net glutamine consumption coupled to urea production in the post-absorptive state, and net glutamin
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Glu Gln Asp and Asn the main amino acids presented
2024-12-24

Glu, Gln, Asp, and Asn, the main Insulin (human) recombinant expressed in yeast presented in the present study, are involved in nitrogen assimilation and transport processes within the plants. Furthermore, they are used to build up reserves during periods of nitrogen availability for subsequent use
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br Adiponectin in prostate cancer
2024-12-24

Adiponectin in prostate cancer PC was documented as the leading type of malignancy in males in the US with respect to both the estimated number of cases (22,800) and deaths (27,540) (Siegel et al., 2016). Studies have reported an association between low APN levels and the progression of PC (Micha
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br Discussion Myopathic EMG changes
2024-12-23

Discussion Myopathic EMG changes are frequently detected in patients with MuSK MG, unlike in AChR MG patients [10]. However, these EMG changes are not always accompanied by myopathic histopathological findings. It has been shown that mitochondrial abnormalities seem to be more prominent in MuSK M
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Firms are subject to corporate taxation and
2024-12-23

Firms are subject to corporate taxation, and face either an ACE or a CBIT tax scheme. The two tax regimes achieve financing neutrality by treating debt and equity equally, but differ according to whether deduction of capital costs from the corporate tax BMS-626529 is allowed or not. While ACE allow
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Human lipoxygenase exists in two
2024-12-23

Human 15-lipoxygenase exists in two forms, named 15-LOX-1 (also named 12/15-LOX, 15-LO-1) and 15-LOX-2. Several reports indicate that 15-LOX-1 has a pathophysiological role in respiratory inflammatory diseases, in particular asthma. Increased activity of 15-LOX-1 is displayed in the respiratory trac
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RAF-1 inhibitor Although the exact mechanisms are not fully
2024-12-23

Although the exact mechanisms are not fully understood, IGF-1 is tightly linked with ER and estrogen actions and a crosstalk occurs between these two systems in breast cancer. To illustrate this close relationship, studies have identified a synergy between IGF-1 and estrogen in RAF-1 inhibitor expr
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Despite the absence of disulfide bonds
2024-12-23

Despite the absence of disulfide bonds in its linear structure, KT43C displays antifungal and antibacterial activity. Disulfide bonds are determinants of defensins' integrity and have been reported to increase the antimicrobial activity (Jenssen et al., 2006). However, some linear derivatives of AMP
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