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Phytophthora capsici is a phytopathogenic oomycete a lineage
2020-09-15
Phytophthora capsici is a phytopathogenic oomycete, a lineage of eukaryotic microorganisms in the kingdom Stramenopila, which causes devastating diseases on many economically important vegetables [15]. Hyps are present in the Phytophthora cell wall proteins [16] and phytotoxic elicitor proteins [17]
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Materials and methods Construction of the Chk YB b
2020-09-15
Materials and methods Construction of the Chk-YB-1b-Neo vector. Approximately 107 plaques from a chicken genomic library established in EMBL3 vector (Clontech Palo Alto, CA) was screened and one clone containing a 12kb insert was selected. Digestion of this clone with SalI and EcoRI restriction enz
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In contrast to drospirenone dydrogestrone acts
2020-09-15
In AH 6809 to drospirenone dydrogestrone acts rather neutral at the aldosterone-, glucocorticoid- and androgen-receptor [12]. This indicates that the assessment of a ‘net-overall effect’ on the vascular system is very difficult based on the often discussed ‘partial effects’ of the progestogens. Thu
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The previously described endogenous patterns of IGF induced
2020-09-15
The previously described endogenous patterns of IGF-1-induced kinase signaling, and resulting interaction between MAPK and PI3K, differ across neuronal sub-types. In R28 retinal neuron-like cells, IGF-1 treatment elicits prolonged activation (at least 80 min) of both PI3K and MAPK (Kong et al., 2016
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Astrocytes play a key role in the brain as
2020-09-15
Astrocytes play a key role in the brain, as these cells are involved in fluid, ion, pH, and neurotransmitter homeostasis, synapse function, energy and metabolism and blood-brain barrier (BBB) maintenance (Sofroniew and Vinters, 2010). PA is able to activate different damaging responses in astrocytes
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br Experimental br Results and discussion On the basis of
2020-09-15
Experimental Results and discussion On the basis of the information obtained from the studies on RHA/TiO2 nanocomposites, it farnesyl diphosphate synthase is expected that this reagent can be used as a catalyst for the promotion of the organic reactions. So this reagent was used in the promot
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In a study performed simultaneously by another group
2020-09-15
In a study performed simultaneously by another group, EWS-FLI-1 introduction into unsorted murine bone marrow-derived cytoskeleton resulted in tumors with various phenotypes including one that is consistent with that of Ewing sarcoma [68]. The tumors expressed markers associated with Ewing sarcoma
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Results are expressed as mean s e m Paired or
2020-09-15
Results are expressed as mean±s.e.m. Paired or unpaired Student\'s t test was used for comparisons between 2 groups and one-way ANOVA followed by Bonferroni\'s post-test for more groups. Statistical significance was assigned if p Results and discussion Variations in [Ca2+]i in cardiomyocytes loade
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Several studies highlighted the potential of EOCs
2020-09-15
Several studies highlighted the potential of EOCs to promote adverse effects on aquatic organisms. It was reported the toxicity of BPA to invertebrates and fish, and the effect of lipophilicity on toxicity was analyzed (Mathieu-Denoncourt et al., 2016). There was reported the effects of PPCPs on aqu
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There are conflicting studies on ET
2020-09-15
There are conflicting studies on ET axis and its relationship with clinicopathologic parameters in various cancers. Endothelin axis expression in the tissue and in blood has been associated with advanced cancer characteristics in colorectal, breast, and prostate cancer, while showing no linkage to c
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br Ubiquitylation of the TGF BMP pathway
2020-09-14
Ubiquitylation of the TGFβ/BMP pathway components Ubiquitylation is a reversible post-translational modification that is essential in many cellular regulatory mechanisms [20], [21]. During the ubiquitylation cascade, ubiquitin is attached to target proteins through the concerted actions of an E1-
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Several reports have exploited the application of HRM for
2020-09-14
Several reports , , , , have exploited the application of HRM for detecting differentially methylated DNA. Even though DNA methylation analysis by HRM cannot determine the methylation status of individual CpGs, it does provide a robust and inexpensive method to differentiate DNA based on the overall
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br Material and methods br Results
2020-09-14
Material and methods Results Discussion Ligase IV is essential for the final ligation of DSBs through the NHEJ pathway. Its co-factor, XRCC4, has been shown to be important for increasing its activity and stability. Interaction between these two factors have been mapped to the linker region
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br Conclusion Our objective is to promote
2020-09-14
Conclusion Our objective is to promote cell activity on biomaterials, especially for use in regenerative medicine, by grafting THPs containing collagen-binding sites onto inert substrates. We have previously reported a methodology to derivatize EDC/NHS crosslinked films with photoreactive THPs. T
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One of the features of ROCO
2020-09-14
One of the features of ROCO proteins, controlled by their domain architecture is their oligomerization status. By size-exclusion chromatography and Western blot analysis, DAPK1 was proved to form homodimers via its GTPase and kinase domains [53]. Similarly, Cy5 TSA Fluorescence System Kit microscopy
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