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Recently dairy proteins obtained from whey have
2024-10-08

Recently, dairy proteins obtained from whey have received considerable attention for their antioxidant bioactivity (Bayram et al., 2008; Haraguchi et al., 2011; Zhang et al., 2012). Bovine whey proteins (WP) are widely used in various foods for their nutritional, health-promoting, and functional val
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br AR expression in breast tissue Although androgenic
2024-10-03

AR expression in breast tissue Although androgenic signalling is chiefly associated with the development and maintenance of primary and secondary male characteristics, especially during puberty when the testes are by far the major source of testosterone, the AR also plays important functions in f
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Introduction Aldose reductase ALR is the first enzyme of
2024-10-03

Introduction Aldose reductase (ALR2) is the first enzyme of the polyol pathway that catalyzes the reduction of glucose to sorbitol utilizing NADPH as a cofactor. The intracellular accumulation of sorbitol, due to increased aldose reductase activity at high blood glucose levels, such as those occurr
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In our previous study we found
2024-10-03

In our previous study we found that the total activity of aldehyde dehydrogenase in cancer Phosind of RCC is at the same level as in normal renal tissue [10]. These findings are similar to our results in serum patients with renal cancer. There is no significant difference between ALDH activity in s
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Brain biopsy was performed from the white matter
2024-10-03

Brain biopsy was performed from the white matter lesion around the posterior horn of the right lateral ventricle, and revealed inflammatory demyelination, such as myelin loss with relative preservation of axons, astrocytosis immnolabeled by WWL 70 australia against glial fibrillary acidic protein, i
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The results show that a tonic action of ACh on
2024-10-03

The results show that a tonic action of ACh on respiration is lacking. However, it is clear that muscarinic cholinergic mechanisms can modulate both eupneic breathing and the cough reflex. When these mechanisms are brought into action is obscure and only tentative proposals can be advanced. ACh in t
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Of note core autophagy factors also play an important
2024-10-01

Of note, core autophagy factors also play an important role during the infection of host cells by another type of picornavirus, namely, echovirus 7. ATG16L1 was found necessary for entry/internalization into Caco-2 polarized epithelial cells because the virus accumulated on the surface of ATG16L1-de
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An alternative more rarely used electron microscopy based ap
2024-10-01

An alternative, more rarely used, electron microscopy-based approach exploits labeling of phagosomes with DAMP (3-(2,4-dinitroanilino)-30-amino-N-methyldipropylamine). DAMP is a weakly basic compound which is membrane-impermeable once it has been protonated. This way, DAMPH+ accumulates in acidic in
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In liver the essential organ of lipoprotein
2024-10-01

In liver, the essential organ of lipoprotein synthesis, ACL plays a fundamental role in lipogenesis and steroidogenesis by supplying cytosolic igf1r inhibitor to both pathways. By using a tricarboxylic acid cycle intermediate (citrate) to produce acetyl CoA, ACL can be seen as an important bridge b
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br Experimental br Acknowledgment This paper was financially
2024-10-01

Experimental Acknowledgment This paper was financially supported by the Project Funded by China Postdoctoral Science Foundation (2017T100186), Natural Science Foundation of Liaoning Province (20170540858), General Scientific Research Projects of Department of Education of Liaoning Province (20
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br Antioxidant polymers conjugates Natural
2024-10-01

Antioxidant-polymers conjugates Natural antioxidants are usually used as a substitute for synthetics but some degradation phenomena could influence their applications. For example, ascorbic alcohol dehydrogenase inhibitor as a natural antioxidant undergoes yellowish coloration as a result of oxi
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Kidney contributes importantly to the long term
2024-10-01

Kidney contributes importantly to the long-term blood pressure control via regulating sodium homeostasis. Renal proximal tubule (RPT) is one of the most critical segments for sodium reabsorption within kidney and therefore involved in blood pressure adjustment. This process is regulated by numerous
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Initially DPP DPP and prolyl tripeptidyl peptidase
2024-10-01

Initially, DPP4, DPP7, and prolyl tripeptidyl peptidase A (PtpA) were the only exopeptidases identified in P. gingivalis. These share substrates according to their altered specificities, as DPP4 is highly specific for Pro at the penultimate position from the N-terminus (P1 position), though it accep
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br Conclusion br Conflict of interest br Acknowledgments We
2024-09-30

Conclusion Conflict of interest Acknowledgments We thank Nancy Kerkvliet for helpful advice. The research in the lab of CE and THS is supported by the Deutsche Forschungsgemeinschaft (grants ES103/7-1 and 9-1, HA7346/2-1). We apologize to all authors whose work could not be cited due to lim
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Here we have used transcriptome analysis of primary
2024-09-30

Here, we have used transcriptome analysis of primary neonatal rat cardiomyocytes treated with either the ETR agonist endothelin-1 or the α1-AR agonist phenylephrine to assess differences in their respective signalling networks, and further probed these differences using a panel of fluorescent resona
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