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A large fraction of UCEs are transcribed T UCEs
2019-11-14
A large fraction of UCEs are transcribed (T-UCEs) in a tissue specific manner, and are deregulated in several human cancers (Calin et al., 2007, Fabbri et al., 2008, Fassan et al., 2014, Olivieri et al., 2016). Indeed, it has been shown that T-UCEs may also act as long non-coding RNAs (lncRNAs) regu
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br Advent of SMEPT br SMEPT for localized synthesis of
2019-11-14
Advent of SMEPT SMEPT for localized synthesis of nitric oxide Critical evaluation and outlook Examples discussed in this review present SMEPT as a methodology for localized drug synthesis – a unique opportunity for site specific therapeutic interventions using implantable biomaterials. This
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Tropical theileriosis is caused by the apicomplexan parasite
2019-11-14
Tropical theileriosis is caused by the apicomplexan parasite Theileria annulata which is transmitted by a tick vector from the genus Hyalomma in cattle (Echebli et al., 2014, Li et al., 2014). Theileria parasites invade the leukocytes by sporozoites secreted from the vector, schizonts mature into me
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Here we report that ILC s sensed
2019-11-14
Here, we report that ILC3s sensed oxysterols through GPR183, which was highly expressed by LTi-like ILC3s. 7α,25-OHC-synthesizing enzymes were produced by fibroblastic stromal Bialaphos sodium salt found in intestinal lymphoid structures, and the GPR183 ligand 7α,25-OHC acted as a chemoattractant fo
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br Conflicts of interest br Financial support NZ is
2019-11-14
Conflicts of interest Financial support NZ is an Established Investigator of the Dutch Heart Foundation (2013T111) and is supported by an ERC Consolidator grant (617376) from the European Research Council and by a Vici grant from the Netherlands Organization for Scientific Research (NWO; 91818
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The photocleaving properties of were studied by performing X
2019-11-14
The photocleaving properties of 1 were studied by performing ΦX174 photocleavage assays. Light irradiation of the mixtures of increasing amounts of 1 with supercoiled DNA caused>90% supercoiled form relaxation and approximately 5% of linearization for the higher concentrations of 1 (1:10bp and 1:2bp
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br Materials and method br Results and
2019-11-14
Materials and method Results and discussion We carried out DNA ligation using free and immobilized T4 DNA ligase in the absence of a magnetic field at 16°C, where the enzyme concentration (final concentration after mixing the solutions for the reaction) in both cases was 0.40μg/mL, and found t
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A number of studies have been carried out
2019-11-13
A number of studies have been carried out to understand lipid production pathways and to increase TAGs level in higher plants. Overexpression of key pitavastatin of the Kennedy pathway until now is by far the most successful strategy to increase TAG lipid content in Brassica napus, Arabidopsis thal
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568 br Materials and methods br Results br Discussion The
2019-11-13
Materials and methods Results Discussion The incretin hormones potently stimulate insulin secretion, and it is generally assumed that this is mediated by an endocrine mechanism such that GIP and GLP-1 through the circulation reach the islet beta 568 to stimulate their secretion. However, t
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Signal transduction through IL c FMS ligand receptor also
2019-11-13
Signal transduction through IL-34/ c-FMS ligand receptor also leads to the differentiation, survival and, angiogenesis, proliferation, adhesion and migration of cells of the monocyte/macrophage lineage similar to that of CSF-1 through the various pathways-First is through FAK (Focal Adhesion Kinase)
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Methylated CpGs can recruit transcriptional co repressors to
2019-11-13
Methylated CpGs can recruit transcriptional co-repressors to prevent transcription factors (TFs) from promoting gene expression by tightly packing ll 37 structures [38]. Two CpG islands in the IPT5b promoter region showed higher methylation level in M9 rootstock compared to Mr (Fig. 3b). However, IP
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According to this theory the chemical potential of the
2019-11-13
According to this theory, the chemical potential of the basic hydrate in the equilibrium condition can be calculated as: , and denote the chemical potentials of the basic hydrate, water and gas, respectively. Also, is the number of gas molecules per water molecules in the basic hydrate. After su
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In studies directed toward the development of sequence speci
2019-11-13
In studies directed toward the development of sequence-specific major-groove binding small Biotin-azide synthesis [11], we desired a non-intercalating molecular scaffold that could direct attached moieties into the major groove. As an initial step toward this goal, we wished to study the DNA bindi
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Within the cluster of North African populations the
2019-11-12
Within the cluster of North African populations the Sousse population sample is somewhat different from the other six populations. One has to analyze more in depth the reasons of this isolation that has been shown by other genetic studies (Fadhlaoui-Zid et al., 2015). It seems that the particular ge
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It is without doubt that the vagina plays
2019-11-12
It is without doubt that the vagina plays a significant role in the perception of coital stimulation leading to sexual arousal and, finally, orgasm. In response to sensory stimulation, relaxation of vaginal vascular and nonvascular smooth muscle occurs, resulting in an increase in local blood flow a
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