Rationale and Conventional Use of Alkylating

2019-08-17

Rationale and Conventional Use of Alkylating Agents and Platinum Derivatives in Clinical Practice After the attack on Bari Harbor in 1943 revealed the effects of mustard gas on bone marrow depletion and the first therapeutic outcomes in lymphoma, alkylating agents gradually became a gold standard as first-line treatment for various cancer indications.

Since both the Ub and ISG15 systems

2019-08-16

Since both the Ub and ISG15 systems are crucial for the innate immune response, many prokaryotic and viral pathogens have evolved ways to hijack them in order to create a “window-of-opportunity” for efficient replication.

At present there have been relatively

2019-08-15

At present, there have been relatively few studies that evaluated potential correlations between pulmonary and pleura metastases, hilar and mediastinal Gardiquimod nodes, and organs associated with distant metastasis and EGFR mutations [33,34,37].

The present work shows that normal climatic

2019-08-14

The present work shows that normal climatic conditions are not critical for the long time survival of DNA in untreated blood stains.

Due to the high attractiveness of E2

2019-08-13

Due to the high attractiveness of E2 and E3 ligases as drug targets, a number of drug discovery assays have been published, based on detection by fluorescence

Hello world!

2018-07-29